Pharmacodynamics Quiz

Froggy Jumps

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Drug action in the body

Creada por

Rehab Abdelrahman

Arabia Saudí

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Froggy Jumps Pharmacodynamics QuizVersión en línea Drug action in the body por Rehab Abdelrahman 1 What describes the relationship between drug concentration and effect at the receptor site? a Pharmacokinetic curve b Therapeutic index line c Concentration–effect (dose–response) relationship 2 Which term best defines ability of a drug to elicit a physiologic response when it interacts with a receptor a Bioavailability b Potency c Efficacy 3 a measure of the amount of drug necessary to produce an effect of a given magnitude. a Potency b Efficacy c Therapeutic index 4 What is EC50? a Maximum effect concentration b 50% of therapeutic index c Concentration producing 50% of the maximal effect 5 Which type of antagonist binds reversibly to the same receptor as the agonist? a Competitive antagonist b Partial agonist c Noncompetitive antagonist 6 What distinguishes a partial agonist from a full agonist? a Partial agonist produces less than maximal effect even at full receptor occupancy b It binds irreversibly c It has no affinity for the receptor 7 Noncompetitive antagonists reduce maximal effect by: a Increasing dissociation rate b Binding to a site other than the active site or irreversible receptor change c Blocking metabolism 8 0+1>1 a Additive effect b Antagonism c Potentiation 9 (Epinephrine antagonizes the effect of histamine, known as a Physiological (functional) antagonism b Chemical antagonism c Pharmacological antagonism 10 Blockers (antagonists) a no affinity, no efficacy b affinity + efficacy c affinity, no efficacy

Froggy Jumps

Pharmacodynamics QuizVersión en línea

Drug action in the body

por Rehab Abdelrahman

What describes the relationship between drug concentration and effect at the receptor site?

Pharmacokinetic curve

Therapeutic index line

Concentration–effect (dose–response) relationship

Which term best defines ability of a drug to elicit a physiologic response when it interacts with a receptor

Bioavailability

Potency

Efficacy

a measure of the amount of drug necessary to produce an effect of a given magnitude.

Potency

Efficacy

Therapeutic index

What is EC50?

Maximum effect concentration

50% of therapeutic index

Concentration producing 50% of the maximal effect

Which type of antagonist binds reversibly to the same receptor as the agonist?

Competitive antagonist

Partial agonist

Noncompetitive antagonist

What distinguishes a partial agonist from a full agonist?

Partial agonist produces less than maximal effect even at full receptor occupancy

It binds irreversibly

It has no affinity for the receptor

Noncompetitive antagonists reduce maximal effect by:

Increasing dissociation rate

Binding to a site other than the active site or irreversible receptor change

Blocking metabolism

0+1>1

Additive effect

Antagonism

Potentiation

(Epinephrine antagonizes the effect of histamine, known as

Physiological (functional) antagonism

Chemical antagonism

Pharmacological antagonism

Blockers (antagonists)

no affinity, no efficacy

affinity + efficacy

affinity, no efficacy

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Pharmacodynamics Quiz

Froggy Jumps

Sobre esta actividad

Creada por

Descarga la versión para jugar en papel

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Pharmacodynamics QuizVersión en línea

por Rehab Abdelrahman

What describes the relationship between drug concentration and effect at the receptor site?

Which term best defines ability of a drug to elicit a physiologic response when it interacts with a receptor

a measure of the amount of drug necessary to produce an effect of a given magnitude.

What is EC50?

Which type of antagonist binds reversibly to the same receptor as the agonist?

What distinguishes a partial agonist from a full agonist?

Noncompetitive antagonists reduce maximal effect by:

0+1>1

(Epinephrine antagonizes the effect of histamine, known as

Blockers (antagonists)

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	Anónimo	%
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