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GI- Phases of digestion and gastric acid secretion

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GI- Phases of digestion and gastric acid secretion

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Fill in the blank for studying BMSC 208

Creada por

Ervine Santiago
Ervine Santiago
Canadá

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GI- Phases of digestion and gastric acid secretionVersión en línea

Fill in the blank for studying BMSC 208

por Ervine Santiago
1

Phases of Digestion : , , ,

2

Cephalic Phase - Initiated by : , taste , thought , swallowing .
Mediated by Stem
Brain Stem Activates : Cranial Nerves : Facial ( ) , ( IX ) , ( X )

3

Cranial Nerve VII and IX - - Stimulate : glands to secrete

4

Nerve : Stimulate : Gastric glands ( ) to secrete juic e

5

Gastric Phase :

Begins : Food reaching

Involves : and Hormonal mechanism

Why ? Promotes : secrection and Gastric motility

6

? Neural regulation
Distension of stimulates
receptors
Chemoreceptors
Activated by :
Increase in

7

Activation of stretch and receptors : Initiates Feedback Loop

Once Nerve impulses reach plexus

Activates : Neurons , Neurons

Increases : Frequency and tone


When Chyme enters during emptying :

It decreases : and pH
Suppression : and Gastric secretio n

8

regulation :
Gastric secretion during gastric phase -
Regulated by :

Gastrin : is released by Cell ( from Gastric glands of the and from ) in Response to :

Distension of stomach ,
Partially digested proteins in chyme ,
High pH of chyme ,
Caffeine , and
ACh released by parasypathetic neurons

9

Gastrin Entering bloodstream : ( reaching the system )
Promotes :
Stimulation : of Gastric glands to gastric juice

Strenghtens : Contraction of esophageal sphincter , prevent of acid into esophagus

Increase : of stomach

Relaxes : sphincter

Activation of : into pepsin

Provides : optimal pH , killing micorbes and denaturing of

10

intestinal Phase :

begins by : entering small intestine

why ?
Inhibitory effects : exit of chyme from stomach
prevents : overloading of
Promotes : Continued

Which involves : Neural and Mechanis m

11

Neural Regulation :

Distension of the

caused by the : Prescne of

Causes : reflex

This Reflex causes : Emptying of from

When receptors send impulses to the medulla oblongta :
- >Inhibition : parasympathetic stimulation , Gastric motility ( which increases : contraction of sphincter - down gastric emptying )

- >Stimulation : nerves to the stomach

12

hormonal regulation of the phase :

is Mediated by : and from small intestine

CCK secreted by cells of glands , in response to : chyme containing amino acids and acids from digested proteins and triglycerides

CCK stimulates : Secretion of Juice , which causes : of Gall bladder , and of Spincter of , which allows : pancreatic juice and to flow inot duodenum

CCK Slows : emptying by : promoting contraction of sphincter ,

CCK Produces : by acting on the hypothalamus

CCK Promotes : growth and maintence of

13

Secretin is

secreted by : cells

Stimulated by : of Acidic chyme

Stimulates : the flow of juice which is rich in -

and inhibits : of gastric juice

and promotes : Growth and maintenance of

14

Which phases initiate Gastric acid : Phase and phase

Cephalic Phase :
Stimulate : glands and gastric glands

During the of the stomach during gastric Phase :
Activates : Gastric Acid secretion

Gastric wall Distensions : Activates : local nervous system , which releases and stimulates parietal cell to secrete more gastric acid

Partially digested proteins or amino acids :
Stimulate : cells that release Gastrin
Gastrin stimulates release of gastric acid and the increase in acid secretion promotes : increase of , digesting more proteins , gastrin release and gastric acid secretion


response and Gastrin release during Cephalic and Gastric phase :
Stimulate : cells from gastric glands to secret histamine
Enhances : release of gastric acid by the cells

Low Intra - Gastric pH :
Stimulates : D cell which release and this release of gastrin by G cells and the net effect is the in gastric acid secretion .

the gastric phase accounts for - of total gastric acid secretio n

 
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