Breast Cancer Markers: Case Study

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Marker-driven therapy decisions

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LAVANYA BALAN

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Breast Cancer Markers: Case Study


Froggy Jumps Breast Cancer Markers: Case StudyVersión en línea Marker-driven therapy decisions por LAVANYA BALAN 1 What cellular marker would be most useful to guide systemic therapy in breast carcinoma patient? a Ki-67 proliferation index b Estrogen receptor (ER) status c HER2/neu status 2 If the tumor is ER-positive, which therapy is commonly used? a Chemotherapy alone b Radiation therapy c Endocrine therapy with tamoxifen or aromatase inhibitors 3 Which test determines hormone receptor status in breast cancer? a Flow cytometry for CD44 b DNA sequencing for BRCA c Immunohistochemistry for ER and PR 4 Which marker's amplification guides the use of trastuzumab? a ER/PR b Ki-67 c HER2/neu 5 Which marker indicates high proliferative activity and can influence prognosis? a HER2 status b ER status c Ki-67 proliferation index 6 Which receptor status must be positive to consider endocrine therapy in this patient? a Triple-negative status b HER2 positivity c Estrogen receptor (ER) positivity 7 Triple-negative breast cancer is defined by the absence of which markers? a ER and PR only b ER, PR, and HER2 c HER2 and ER only 8 What subtype is defined by invasion from the carcinoma breaching the basement membrane into surrounding tissue? a Invasive ductal carcinoma b Ductal carcinoma in situ c Lobular carcinoma in situ 9 Which marker is studied when a patient's first degree relative has breast carcinoma ? a Ki-67 proliferation index b HER2 status c BRCA mutation status 10 What targeted therapy is specifically used for HER2-positive tumors? a Tamoxifen b Trastuzumab c Aromatase inhibitors 11 What targeted therapy is specifically used for HER2-positive tumors? a Tamoxifen b Trastuzumab c Aromatase inhibitors 12 indian file pattern is seen in which carcinoma a lobular carcinoma b invasive breast carcinoma NOS c mucinous carcinoma 13 Carcinoma with with dilated ducts and central zone of necrosis a colloid carcinoma b ductal carcinoma insitu comedo carcinoma type c tubular carcinoma 14 All mutations are seen in breast carcinoma except a BRCA1, BRCA2 b Tp53, PTEN c NF1,NF2 15 molecular subtypes of breast carcinoma are all except a Luminal A, Luminal B b HER2 positive, Triple negative c Luminal C

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Breast Cancer Markers: Case Study

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Breast Cancer Markers: Case StudyVersión en línea

por LAVANYA BALAN

What cellular marker would be most useful to guide systemic therapy in breast carcinoma patient?

If the tumor is ER-positive, which therapy is commonly used?

Which test determines hormone receptor status in breast cancer?

Which marker's amplification guides the use of trastuzumab?

Which marker indicates high proliferative activity and can influence prognosis?

Which receptor status must be positive to consider endocrine therapy in this patient?

Triple-negative breast cancer is defined by the absence of which markers?

What subtype is defined by invasion from the carcinoma breaching the basement membrane into surrounding tissue?

Which marker is studied when a patient's first degree relative has breast carcinoma ?

What targeted therapy is specifically used for HER2-positive tumors?

What targeted therapy is specifically used for HER2-positive tumors?

indian file pattern is seen in which carcinoma

Carcinoma with with dilated ducts and central zone of necrosis

All mutations are seen in breast carcinoma except

molecular subtypes of breast carcinoma are all except