Graft vs Host Disease

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GVHD series of questions

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Mishal Amir

Reino Unido

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Froggy Jumps Graft vs Host DiseaseVersión en línea GVHD series of questions por Mishal Amir 1 What is the ‘graft’ in graft vs host disease? a Transplant recipient b Transplanted donor immune cells c 2 What molecules are crucial for the graft recognising host immune cells as 'non-self'? a MHC I, MHC II b MHC I only c MHC II only 3 GVHD is primarily mediated by which immune cells? a T cells b B cells c Macrophages 4 Which hypersensitivity reaction is GVHD classed as? a Type III b Type II c Type IV 5 There are 3 requirements to develop GVHD. Which are they? a Donor antibodies bind to host tissues, Immunocompromised host, Host t-cells recognise donor antigens b Graft contains T cells, Immunocompromised host, Host and donor are HLA-mismatched c Circulating immune complexes, Immunocompromised host, Mismatch of ABO blood groups, 6 There is Acute and chronic GVHD. After how many months after a transplant, can the GVHD be labelled as “chronic?” a 6 b 8 c 3 7 Acute GVHD typically affects 3 organs? Which ones are they? a Skin, Liver, Gut b Skin, Lungs, Eyes c Skin, Gut, Muscles

Froggy Jumps

Graft vs Host DiseaseVersión en línea

GVHD series of questions

por Mishal Amir

What is the ‘graft’ in graft vs host disease?

Transplant recipient

Transplanted donor immune cells

What molecules are crucial for the graft recognising host immune cells as 'non-self'?

MHC I, MHC II

MHC I only

MHC II only

GVHD is primarily mediated by which immune cells?

T cells

B cells

Macrophages

Which hypersensitivity reaction is GVHD classed as?

Type III

Type II

Type IV

There are 3 requirements to develop GVHD. Which are they?

Donor antibodies bind to host tissues, Immunocompromised host, Host t-cells recognise donor antigens

Graft contains T cells, Immunocompromised host, Host and donor are HLA-mismatched

Circulating immune complexes, Immunocompromised host, Mismatch of ABO blood groups,

There is Acute and chronic GVHD. After how many months after a transplant, can the GVHD be labelled as “chronic?”

Acute GVHD typically affects 3 organs? Which ones are they?

Skin, Liver, Gut

Skin, Lungs, Eyes

Skin, Gut, Muscles

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Graft vs Host Disease

Froggy Jumps

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Froggy Jumps

Graft vs Host DiseaseVersión en línea

por Mishal Amir

What is the ‘graft’ in graft vs host disease?

What molecules are crucial for the graft recognising host immune cells as 'non-self'?

GVHD is primarily mediated by which immune cells?

Which hypersensitivity reaction is GVHD classed as?

There are 3 requirements to develop GVHD. Which are they?

There is Acute and chronic GVHD. After how many months after a transplant, can the GVHD be labelled as “chronic?”

Acute GVHD typically affects 3 organs? Which ones are they?

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