Complement System Quiz

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Test your knowledge of the complement pathways and functions.

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Quader Ahmed Jalili

India

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Complement System Quiz


Froggy Jumps Complement System QuizVersión en línea Test your knowledge of the complement pathways and functions. por Quader Ahmed Jalili 1 Which pathway is activated by antibodies and antigen–antibody complex? a Lectin pathway b Classical pathway c Alternative pathway 2 What initiates the classical pathway? a Virus binding b Antigen–antibody complex c C3b deposition 3 Which molecule marks the initiation of the lectin pathway? a MBL binding to mannose residues b Properdin binding c C1q binding 4 Which component forms the C3 convertase in the classical pathway? a C4b2a b C1qrs c C3bBb 5 Which molecule stabilizes the alternative pathway C3 convertase? a Properdin b C2a c Factor D 6 What is the key product of MAC formation? a Opsonization b Viral neutralization c Target cell lysis 7 Which anaphylatoxins are produced during activation? a MAC b C1q, C2 c C3a, C4a, C5a 8 Which process removes immune complexes from blood? a Antibody production b Complement-mediated removal c Phagocytosis exclusively 9 Which function enhances viral neutralization by coating viruses? a Antibody class switching b T-cell killing c Complement coating on virus surfaces 10 Which pathway is activated by microbial surfaces without antibodies? a Alternative pathway b Classical pathway c Lectin pathway 11 What role do C3a, C4a, and C5a play in inflammation? a Suppress inflammation b Promote clotting only c Cause vasoconstriction and increased permeability 12 Which component is inhibited by C1 inhibitor? a Lectin pathway b Alternative pathway c Classical pathway 13 Which molecule accelerates dissociation of C3 convertase on cell membranes? a C1 esterase inhibitor b DAF (CD55) c Properdin 14 What is the major outcome of MAC on target cells? a Opsonization b Viral neutralization c Lysis 15 Which complement pathway involves C4b2a as C3 convertase? a Lectin pathway b Classical pathway c Alternative pathway 16 Which convertase is formed by the alternative pathway? a C4b2a b C3bBb c C3bBbC2a 17 Which regulator is a membrane-bound molecule that inhibits all three pathways? a Factor H b DAF (CD55) c C1 inhibitor 18 Which step directly leads to opsonization? a C3b deposition on surfaces b C1q binding c MAC formation 19 Which virus-retaining mechanism involves the complement system? a Phagocytosis only b Antibody production c Viral neutralization 20 Which pathway is initiated by mannose-binding lectin complexes? a Alternative pathway b Classical pathway c Lectin pathway 21 Which enzyme complex is named as C3 convertase in the lectin pathway? a C4b2a b C1qrs c C3bBb 22 Which component is released as an anaphylatoxin in the classical pathway? a C3a b C5a c C4a 23 What is the general purpose of complement regulation? a Only activate pathogens b Limit activity to target cells c Amplify all immune responses 24 Which component is the major opsonin in many pathways? a C1q b MASP c C3b 25 Which pathway directly leads to MAC assembly on microbes? a All three pathways contribute to MAC b Only classical pathway c Only lectin pathway

Complement System Quiz

Froggy Jumps

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Complement System QuizVersión en línea

por Quader Ahmed Jalili

Which pathway is activated by antibodies and antigen–antibody complex?

What initiates the classical pathway?

Which molecule marks the initiation of the lectin pathway?

Which component forms the C3 convertase in the classical pathway?

Which molecule stabilizes the alternative pathway C3 convertase?

What is the key product of MAC formation?

Which anaphylatoxins are produced during activation?

Which process removes immune complexes from blood?

Which function enhances viral neutralization by coating viruses?

Which pathway is activated by microbial surfaces without antibodies?

What role do C3a, C4a, and C5a play in inflammation?

Which component is inhibited by C1 inhibitor?

Which molecule accelerates dissociation of C3 convertase on cell membranes?

What is the major outcome of MAC on target cells?

Which complement pathway involves C4b2a as C3 convertase?

Which convertase is formed by the alternative pathway?

Which regulator is a membrane-bound molecule that inhibits all three pathways?

Which step directly leads to opsonization?

Which virus-retaining mechanism involves the complement system?

Which pathway is initiated by mannose-binding lectin complexes?

Which enzyme complex is named as C3 convertase in the lectin pathway?

Which component is released as an anaphylatoxin in the classical pathway?

What is the general purpose of complement regulation?

Which component is the major opsonin in many pathways?

Which pathway directly leads to MAC assembly on microbes?