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Reading-Science-1

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Reading-Science-1

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por Nguyen Huy Vu
1

The chemical formula of deoxyribonucleic acid ( DNA ) is now well established . The molecule is a very long chain , the of which consists of a regular of sugar and phosphate groups . To each sugar is a base , which can be of four different types . Two of the possible bases ? and guanine ? are purines , and the other two ? and cytosine ? are pyrimidines . So far as is known , the of bases along the chain is irregular . The unit , consisting of phosphate , sugar and base , is known as a nucleotide .

2

The first feature of our structure which is of biological interest is that it consists not of one chain , but of two . These two chains are both around a common fiber . It has often been assumed that since there was only one chain in the chemical formula there would only be one in the structural unit . However , the , taken with the X - ray evidence , suggests very strongly that there are two .

3

We believe that the bases will be present almost entirely in their most probable forms . If this is true , the conditions for forming hydrogen are more restrictive , and the only pairs of bases possible are : adenine with thymine , and guanine with cytosine . Adenine , for example , can occur on either chain ; but when it does , its on the other chain must always be thymine .

4

The phosphate - sugar backbone of our model is completely regular , but any sequence of the pairs of bases can fit into the structure . It follows that in a long molecule many different are possible , and it therefore seems likely that the sequence of bases is the code which carries the information . If the actual order of the bases on one of the pair of chains were given , one could write down the exact order of the bases on the other one , because of the specific pairing . Thus one chain is , as it were , the of the other , and it is this feature which suggests how the deoxyribonucleic acid molecule might itself .

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