Pharmacogenomics Quiz

Froggy Jumps

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Test your gene-drug knowledge.

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Feda

Emiratos Árabes Unidos

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Froggy Jumps Pharmacogenomics QuizVersión en línea Test your gene-drug knowledge. por Feda 1 What genetic test is used to guide drug choice and dosing? a Routine blood type testing b Pharmacogenomic testing. c Allergy testing 2 patient’s specific combination of alleles for a particular gene (e.g., CYP2D6 1/2) is referred to as their: a Genotype b Haplotype c Diplotype 3 The observable clinical trait resulting from a person’s DNA, such as being a “poor metabolizer,” is known as their: a Phenotype b Genotype c Haplotype 4 Which best defines a genetic polymorphism? a Any DNA change that causes disease b A DNA variant with minor allele frequency ≥1% c A de novo variant in one family 5 Which option best illustrates copy-number variation (CNV)? a CYP2D6 5 (gene deletion) b CYP2C19 c.681G>A c A promoter (TA) repeat 6 Which gene is most directly linked to pharmacokinetics? a VKORC1 b HLA-B c CYP2C19 7 Polymorphism vs mutation—choose the most accurate statement: a Polymorphisms are always pathogenic b Polymorphisms are common variants; many are benign c Mutations are common (≥1%); polymorphisms are rare 8 Which of the following is a classic SNP notation? a CYP2C19 c.681G>A b UGT1A1 (TA)7 c CYP2D6 5 9 A kidney transplant recipient with a CYP3A5 1/1 genotype is an extensive metabolizer of tacrolimus. This patient will likely require: a No tacrolimus at all. b A switch to cyclosporine. c A significantly higher starting dose of tacrolimus.

Froggy Jumps

Pharmacogenomics QuizVersión en línea

Test your gene-drug knowledge.

por Feda

What genetic test is used to guide drug choice and dosing?

Routine blood type testing

Pharmacogenomic testing.

Allergy testing

patient’s specific combination of alleles for a particular gene (e.g., CYP2D6 1/2) is referred to as their:

Genotype

Haplotype

Diplotype

The observable clinical trait resulting from a person’s DNA, such as being a “poor metabolizer,” is known as their:

Phenotype

Genotype

Haplotype

Which best defines a genetic polymorphism?

Any DNA change that causes disease

A DNA variant with minor allele frequency ≥1%

A de novo variant in one family

Which option best illustrates copy-number variation (CNV)?

CYP2D6 *5 (gene deletion)

CYP2C19 c.681G>A

A promoter (TA) repeat

Which gene is most directly linked to pharmacokinetics?

VKORC1

HLA-B

CYP2C19

Polymorphism vs mutation—choose the most accurate statement:

Polymorphisms are always pathogenic

Polymorphisms are common variants; many are benign

Mutations are common (≥1%); polymorphisms are rare

Which of the following is a classic SNP notation?

CYP2C19 c.681G>A

UGT1A1 (TA)7

CYP2D6 *5

A kidney transplant recipient with a CYP3A5 1/1 genotype is an extensive metabolizer of tacrolimus. This patient will likely require:

No tacrolimus at all.

A switch to cyclosporine.

A significantly higher starting dose of tacrolimus.

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Pharmacogenomics Quiz

Froggy Jumps

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Pharmacogenomics QuizVersión en línea

por Feda

What genetic test is used to guide drug choice and dosing?

patient’s specific combination of alleles for a particular gene (e.g., CYP2D6 1/2) is referred to as their:

The observable clinical trait resulting from a person’s DNA, such as being a “poor metabolizer,” is known as their:

Which best defines a genetic polymorphism?

Which option best illustrates copy-number variation (CNV)?

Which gene is most directly linked to pharmacokinetics?

Polymorphism vs mutation—choose the most accurate statement:

Which of the following is a classic SNP notation?

A kidney transplant recipient with a CYP3A5 1/1 genotype is an extensive metabolizer of tacrolimus. This patient will likely require:

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Pharmacogenomics Quiz

Froggy Jumps

Sobre esta actividad

Creada por

Descarga la versión para jugar en papel

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Pharmacogenomics QuizVersión en línea

por Feda

What genetic test is used to guide drug choice and dosing?

patient’s specific combination of alleles for a particular gene (e.g., CYP2D6 *1/*2) is referred to as their:

The observable clinical trait resulting from a person’s DNA, such as being a “poor metabolizer,” is known as their:

Which best defines a genetic polymorphism?

Which option best illustrates copy-number variation (CNV)?

Which gene is most directly linked to pharmacokinetics?

Polymorphism vs mutation—choose the most accurate statement:

Which of the following is a classic SNP notation?

A kidney transplant recipient with a CYP3A5 *1/*1 genotype is an extensive metabolizer of tacrolimus. This patient will likely require:

patient’s specific combination of alleles for a particular gene (e.g., CYP2D6 1/2) is referred to as their:

A kidney transplant recipient with a CYP3A5 1/1 genotype is an extensive metabolizer of tacrolimus. This patient will likely require: