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Urinary system

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Urinary system

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Urinary System what u need to know.

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Urinary system
 

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Urinary systemVersión en línea

Urinary System what u need to know.

por Yeslin Santos
1

erythropoietin production internal base environment regulating pressure renin toxins vitamin wastes Gluconeogenesis ions solutes ECF calcitriol ions metabolic osmolarity regulating excess D blood volume fastin water acid blood body RBC

* Removal of , , and from the
* Maintain the ? s :
* Regulate total and ( concentration of ) of the body
* Regulate concentrations of in ( ex . Na + , K + , Ca + , Cl - )
* Maintain - balance
* Hormone production ( for and for )
* Converts to ( its active form )
* during prolonged

2

bladder Urinary Nephrons Ureters Kidneys Urethra

* are major excretory organs
- are the functional excretory units
* is the temporary storage reservoir for urine
* transport urine from the kidneys to the bladder
* transports urine out of the bod y

3

hilum sinus lumbar Convex nerves hilu blood superior vessels Retroperitoneal concave left Ureters renal Right lymphatics

The Kidneys
* , in the region
* kidney is lower than the
* lateral surface , medial surface
* Renal leads to the renal
* , , , and enter and exit at the

4

Renal Cortex Renal calyx Medulla Column Renal Superficial Minor Renal Pelvis

: Contains bulk of nephron structures ; region of kidney

: Containing mostly
collecting ducts

: Runs between each medulla

: Cup shaped , encircles the apex of a pyramid

- Basin area of kidney , continuous with urete r

5

urine functional 85% wate Renal tubule Nephrons long conserving cortex interface Glomerulus 1 Cortical corpuscle Juxtamedullary loops Nephrons urine capsule units capillaries renal Bowman concentrated medulla

The Nephron :
Structural and that form
Each kidney contains about million nephrons

Two main parts :
- ( ) : a tuft of
- : begins as cup - shaped glomerular ( ? s ) surrounding the glomerulus


Two Classes
- : About of all nephrons , almost completely in cortex

- : Originate at - , that dip into the medulla ; allow for production of &

6

DCT cortical capillaries PCT juxtamedullary recta Peritubular Vasa

Two Classes
Cortical Nephrons :
associated with and of nephrons

Juxtamedullary Nephrons :
associated with the nephron loop of nephron s

7

cells ascending nephron Juxtaglomerular NaCl walls convoluted densa systemic Complex distal ascending communication blood blood macula arteriole Juxtaglomerular JGC filtrate densa cells Juxtaglomerular cells signal tubule Granular Complex Macula arterioles pressure cells arteriole JGC pressure Complex afferent concentrations chemoreceptor JGC mesangial formation chemical afferent loop renin Extraglomerular mechanoreceptors glomerulus granular

* ( ) : Region where portion of nephron loop lies against the that feeds the

* ( ) : Both the and cells are modified at point of contact

* ( ) helps to regulate rate of &

* ? modified cells of nephron loop ; packed beside granular cells ; cells that monitor of filtrate entering the

* ? found in ; act as , releasing when changes in occur

* ? lie between the nephron loop and arterioles ; allows between and via

8

Chemically wastes pathology 95% Abnormally urine 5% filtered formation cleansing urine high balancing Nitrogenous blood

* water and solutes

* : urea , uric acid , and creatinine

* Other normal solutes
Na + , K + , PO43 ? , and SO42 ? ,
Ca2 + , Mg2 + and HCO3 ?

* concentrations of any constituent may indicate

* and of the blood leads to ? is literally just !

9

Tubular filtration Tubular secretion reabsorption Glomerular

* : " dumping filtrate into the waste container "

* : " reclaiming what the body needs to keep "

* : " selectively adding to the waste container "

10

water i solutes solutes pressure Net osmotic water Colloid outward Filtration pressure formation filtrate out Pressure inward Hydrostatic

* is determined by the differences in and pressures

* of the glomerular capillaries ( HPgc ) aka glomerular BP , promotes , " the push " forcing and of blood

* of the glomerular capillaries ( OPgc ) , " the pull " by blood proteins keeping and

11

magnesium infection acid calcium Kidney pH pressure urine chronic stones uric pain Ca2 ureter bacterial

* form in renal pelvis
- Crystallized , , or salts
* Larger stones block , cause and in kidneys
* May be due to , retention , ? + in blood , ? of urin e

12

Micturition

: Urination or voidin g

13

sphincter syste urethral detrusor nervous ANS ANS external internal muscle somatic sphincter urethral

Three simultaneous events
* Contraction of by
* Opening of by
* Opening of by

14

diet 1 2 180 output urine 0 cellular metabolism 8 24 30 Urinalysis urinary Urinalysis consistancy 150

* Blood composition depends on : , and

* In hours , million nephrons of the kidneys filter - liters of blood plasma ; resulting in . - liter of urine output daily
* In healthy individuals , kidneys maintain despite variation in diet and metabolic activity

* allows testing to determine substances present in a urine specimen ? this can be used to assess health of a patient

* must be done within minutes after urine is voide d

15

Color Transparency urine Odor gravity pH of Specific

* and

* ? slightly aromatic

* ranges from 4 . 5 - 8 . 0 ( average of 6 )

* is the relative weight of a specific volume of liquid compared with an equal volume of distilled water . The specific gravity of distilled water is 1 . 000 , because 1 ml weighs 1 gram .

16

bile foods drugs UT clear yellow Color urochrome amber water blood solutes pale Transparency

* and

* Should be and to in color , due to ( pigment metabolite of bilirubin )

* Color variations indicate the relative concentration of to in the urine

* Abnormal urine color may be due to certain , such as beets , various , , or

* Cloudy urine may indicate a

17

urinary pH Diet pH urine vegetables urine acidity whole vegetarian urine Bacteria urine acid 8 4 infection Odor 0 wheat urine disease 5 odor drugs 6 of diet odor pH increase ammonia ash tract urine alkalinity protein

* ? slightly aromatic
- action gives it an - like
- Some , and various processes alter the characteristic or .
Example : someone with uncontrolled diabetes mellitus makes urine smell fruity or acetone - like .

* ranges from . - . ( average of )
* can influence or
- A diet high in and raise the of . The foods that can
the are called foods .
- A ( alkaline ash diet ) increases the of the .
- A may also result in urine with a high pH .

18

less precipitate volume 1 water hydrometer 001 Specific distilled stones kidney volume solutes 1 equal urinprober crystallize 1 ml liquid more 000 030 1 gravity 1 specific

* is the relative weight of a of compared with an of . The specific gravity of distilled water is . , because weighs gram .

- Measured using a /
- Urine weighs more because it has ? normal is . - . .

- High specific gravity = solutes
Limited fluid intake , fever , kidney inflammation

- Low specific gravity = solutes
Excessive water intake , diabetes insipidus or chronic renal failure

* If urine becomes excessively concentrated , some substances normally held in solution begin to or forming ( renal calculi ) .

19

collecting pathological distal Casts convoluted blood Hardened white cell Hyaline ducts blood cell tubules red

:
* cell fragments , formed in &
* , and casts
* Always indicate a conditio n

20

mellitus mechanisms Glucosuria diabetes carbohydrate active blood inadequate Glycosuri High Glucose sugar insulin transport exceeded levels

( ) :
* due to levels ; or can result when for glucose are temporarily
* Excessive intake
* Uncontrolled
* Aka

21

increased trauma intake Albumin kidney permeability Hypertension glomerulus overabundant protein Poisons big excessive pregnancy exertion Pathological Toxins

* - albumin in urine

- Normally albumin is too to pass through the ? so when it does you have an abnormally of the membrane .

- Nonpathological conditions :
, ,

- conditions usually events that damage the glomerular membrane
*
*
*
*

22

beta diets ketone metabolic starvation abnormal fat mellitu acidosis acid hydroxybutyric small diabetes acid larger acetone glucose ketones carbohydrates bodies

* Ketone Bodies ( Ketonuria ) :
Acetoacetic , - and are .

- Normally found in amounts in urine

- If amounts usually indicates processes are occurring . The result is .

- Expect to see this during or very low in ? inadequate food forces the body to use its stored .

- Finding both and usually indicates

23

big pathology Blood rbc Red Cells

* ( hematuria ) :
Indicates of the urinary tract ? are too to pass through glomerular pores

- Kidney stones
- Infection
- Tumors
- Physical trauma to urinary organ s

24

RBCs hemolysis Hemoglobin

* ( Hemoglobinuria ) in urine as a result of ( bursting ) of

* Indicates
- Hemolytic anemias
- Transfusion reactions
- Burns
- Venomous snake bites
- Renal diseas e

25

bacterial infection pathology urinary urine inflammation Pigments Bile liver White Blood yellow bladder Nitrites trac foam Cells shaken infection

*
- May indicate a ( E . coli )
- Valuable for early indicators of

* ( Bilirubinuria ) bilirubin in urine ( bile pigments )
Usually indicates
- hepatitis
- cirrhosis
- bile duct blockage
Usually forms when urine is

* ( Pyuria ) presence of white blood cells in ( pus )
- Indicates of

26

Diabetes Glomerulonephritis mellitus Gonorrhea insipidus Pyelonephritis Diabetes

* - kidney infection

* - " glomerular disease " acute inflammation of the kidney , typically caused by an immune response

* - sexually transmitted bacterial infection

* - diabetes - too much sugar in the blood

* - rare - caused by a deficiency of the pituitary hormone ADH ( vasopressin ) which regulates kidney function .

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