Relacionar Columnas HISTOLOGY: Bones, cartilage, joints, lesson 3Versión en línea MIDTERM por Danillee Faye Mabayag 1 Lamellar bone (Synonyms) 2 Woven bone (SYNONYMS) 3 Lamellar bone (Characteristics) 4 Woven bone (Characteristics) 5 Woven bone (Major location) 6 LAMELLAR vs WOVEN BONE 7 Lamellar bone (Location) LAMELLAR vs WOVEN BONE Parallel organized collagen in thin layers (lamellae); regularly spaced cells; heavily calcified All normal regions in adult bone Developing and growing bones; hard callus of bone fractures Immature, Primary, Bundle bone, newly calcified Irregular and random collagen. Lightly calcified Mature bone; 2ndary bone 1 Cancellous bone (Location) 2 Cancellous bone (Synonyms) 3 Compact bone (Characteristics) 4 Compact VS Cancellous bone 5 Compact bone (synonyms) 6 Cancellous bone (Characteristics) 7 Compact bone (Location) Inner region of bones, adjacent to marrow cavities Compact VS Cancellous bone 20% of all lamellar bone; Spongy bone; TRABECULAE; bone; Medullary bone 80% of all lamellar bone, Cortical bone Interconnected thin spicules/ trabeculae covered by endosteum Thick, outer region (beneath periosteum) of bones Parallel lamellae or DENSEpacked osteons, w. interstitial lamellae 1 Hyaline cartilage (Type 2)(Organ) 2 Hyaline cartilage (perichondrium) 3 Elastic cartilage 4 Fibrocartilage 5 Fibrocartilage (Type 1 predominant) (Organ) 6 Elastic cartilage (Type 2) (Organ) Has perichondrium (except epiphyses and articular cartilage) External EAR; External acoustic meatus, auditory tube'; EPIGLOTTISand other laryngeal cartilage, AURICLE, EUSTACHIAN TUBE BRONCHI; TRACHEA; Articular ends and EPIPHYSEAL PLATE of long bones; Fetal skeleton; ARTICULAR and COSTAL cartilage; Has perichondrium Intervertebral disc; Pubic symphysis; meniscus; insertion of tendon NO PERICHONDRIUM 1 Elastic cartilage (Type 2) 2 Fibrocartilage (Type 1) 3 Hyaline cartilage (Type 2) Glassy, smooth, homogenous, structural support, low friction surface in joints; respiratory tract, aggrecan Type 1 predominantly but has small type 2, cushion, tensile strength and resistance to tear Flexible , dark elastic fibers, aggrecan 1 Vesicular zone 2 Basal zone 3 4 REGIONS in ELECTRON MICROSCOPY 4 Clear zone 5 Ruffled border Exocytotic vesicles (transfer lysosomal enzymes) ; Endocytotic vesicles (transfer degraded bone); Enzyme product transport 4 REGIONS in ELECTRON MICROSCOPY Attachment/sealing ; MICROFILAMENTS opposite of ruffled border; MOST CELL ORGANELLES Active bone RESORPTION (irregular finger like cytoplasmic extend to Howship) 1 Proliferative zone 2 Ossification zone 3 Resting zone 4 2NDARY CENTER OF OSSIFICATION 5 Calcified zone 6 Hypertrophic zone Chondrocytes DIVIDE into columns 2NDARY CENTER OF OSSIFICATION Hyaline cartilage swollen, enlarged degenerative chondrocytes loss of chondrocytes + calcification Bone tissue first appears (osteoblast lay bone) 1 Osteoprogenitor 2 Osteocyte 3 Osteoclast 4 Osteoblast Maintains bone; In lacunae, processes in canaliculi' Regular spaced matrix; flat-almond shape, less RER Stem/precursor cell; Gives rise to osteoblast builds bone; Cuboidal, basophilic, osteoid nearby; like PLASMA CELL; ECCENTRIC NUCLEUS Resorbs bone; Large, MULTINUCLEATED, howship lacunae; DESTRUCTION 1 Periosteum 2 Type 2 collagen 3 Type 1 collagen 4 Intramembranous 5 Endochondral 6 Primary center 7 M-CSF and RANKL 8 Secondary center 9 Osteon 10 Volkmann canals 11 Osteocalcin Nourish osseous tissue (oppositional bone growth + trabeculae) Noncollagen secreted by osteoblast rich in ALP; serve as foci for HYDROXYAPATITE CRYSTAL Complex; haversian system 2 polypeptides produced by osteoblast Epiphysis Bone + fibrocartilage Hyaline + elastic cartilage Perforating canals Flat skull bones Most long bones; primary center in diaphysis, secondary center in epiphysis Diaphysis 1 Calcium hydroxyapatite 2 Cement line 3 Type 1 collagen, proteoglycan aggregates; bone-specific multiadhesive glycoproteins 4 Osteon (Haversian system) 5 Concentric lamellae 6 Articular cartilage 7 Regulates hyaline cartilage 8 Howship lacunae or Resorption cavity Organic matter composed of Movable joints; lacks perichondrium; diffusion of O2 and nutrients supporting structure; an osteon (haversian system) Outer boundary of each osteon complex of concentric lamellae; bifurcated cylinder areas of bone undergoing resorption, osteoclast lie in depression or cavities Most abundant in bone matrix Growth hormone and somatotropin (indirect, insuline like) and somatomedins (direct proliferation) 1 Diarthroses 2 Symphyses 3 Synostoses 4 Synarthroses 5 Syndesmose Free bone movement; Synovial fluid is made up of HYALURONAN Very limited or no movement Immobile joints w/ pad of fibrocartilage between articular cartilage; ALL SYMPHYSES, PUBIC SYMPHYSIS, usually in midline United only by bone tx and no movement; SUTURES, thin layers of CT w/ osteogenic cells Join bones by dense CT only; INTEROSSEOUS LIGAMENT of inferior tibiofibular joint and posterior SARCROILIAC joints