Antimicrobial Pharmacology

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Clinical application

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Amanda

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Antimicrobial Pharmacology


Antimicrobial PharmacologyVersión en línea Clinical application por Amanda 1 If a pt has a severe gram negative infection, what antibiotic would you expect to see? a Gentamicin b Metronidazole c Vancomycin d Erythromycin 2 If a pt has a protozoa infection, what order would you expect for them to have? a Metronidazole b Vancomycin c Gentamicin d Linezolid 3 What order would you expect to see for a pt with a gram positive infection? a Vancomycin b Meteronidazole c Gentamicin d Clindamycin 4 What order should the nurse question for a patient with a bacterial infection with a hx of HTN currently taking furosemide? a Gentamicin b Vancomycin c Erythromycin 5 What order should the nurse question for a pt with HTN currently taking lisinopril? a Vancomycin b Erythromycin c Gentamicin 6 What order should the nurse question for a pt with depression who's currently taking an SSRI and a bacterial infection? a Erythromycin b Vancomycin c Gentamicin 7 What color do you think of for a pt with tuberculosis Choose one or more answers a orange - red-orange tinged bodily fluids b purple c orange - RIPE d green - green tinged bodily fluids 8 Which medication would you give for a pt with penicillinase-producing staphyloccoci/streptococci a Oxacillin b Amoxicillin c Piperacillin-tazobactam d Cefazolin 9 Which medication is ONLY used for SERIOUS gram - infections a Gentamicin b Tetracycline c Erythromycin 10 Which medication binds to sterols in the fungal cell wall membrane? a Fluconazole (Azoles) b Micafungin (Echinocandin) 11 Which medication inhibits glucan synthesis (an enzyme present in the fungal cell wall) a Micafungin (Echinocandin) b Fluconazole (Azoles) 12 Which medication would you see an order for to treat a fungal infection - ONLY IN THE HOSPITAL SETTING a Amphotericin B (Nucleoside Analogue) b Micafungin (Echinocandin) 13 Which adverse effects would you expect to see in a patient taking an antifungal medication Choose one or more answers a Liver damage b GI effects c Renal damage d Bone marrow supression e Dermatological reactions 14 Amphoterincin B contraindication Choose one or more answers a NSAIDs b pregnancy c Liver/renal disease d Endocrine disorder e GERD 15 Which medication class has many interactions due to it's inhibition of the P450 family of enzymes a Azoles b Echinocandins c Nucleoside Analogues 16 Which order would the nurse expect to see for a patient who was diagnosed with influenza A (or avian flu) within the last 26 hours? a Oseltamivir (Neuraminidase Inhibitor) b Acyclovir (Nucleoside Analogue) c Remdesivir (Nucleoside Analogue) 17 Which medication order should the nurse expect to see for a patient with HSV or Varicella-Zoster to inhibit the viral DNA replication? a Acyclovir (Nucleoside Analogue) b Oseltamivir (Neuraminidase Inhibitor) c Remdesivir (Nucleoside Analogue) 18 Which medication order should the nurse expect to see for a patient with Covid-19 to inhibit the RNA polymerase enzyme that is used for viral RNA synthesis? a Remdesivir (Nucleoside Analogue) b Acyclovir (Nucleoside Analogue) c Oseltamivir (Neuraminidase Inhibitor) 19 What should the nurse recognize is a contraindication for antiviral therapy? a Severe CNS disorders b Hypertension c Heart failure d Pneumocystis jiroveci 20 HIV/AIDS meds: fusion inhibitor MOA a Prevents fusion of the HIV-1 virus with the human cellular membrane, preventing it from entering the cell b Blocks the CCR5 receptor site on the T-cell membrane that the HIV virus needs to interact with to enter the cell c Inhibits the activity of integrase, an encoded enzyme needed for viral replication, preventing the formation of the HIV-1 provirus 21 HIV/AIDS meds: integrase strand transfer inhibitor MOA a Inhibits the activity of integrase, an encoded enzyme needed for viral replication, preventing the formation of the HIV-1 provirus b Prevents fusion of the HIV-1 virus with the human cellular membrane, preventing it from entering the cell c Blocks the CCR5 receptor site on the T-cell membrane that the HIV virus needs to interact with to enter the cell 22 HIV/AIDS meds: CCR5 coreceptor antagonist MOA a Blocks the CCR5 receptor site on the T-cell membrane that the HIV virus needs to interact with to enter the cell b Prevents fusion of the HIV-1 virus with the human cellular membrane, preventing it from entering the cell c Inhibits the activity of integrase, an encoded enzyme needed for viral replication, preventing the formation of the HIV-1 provirus 23 HIV/AIDS meds: Nonnucleoside reverse transcriptase inhibitors (NNRTIs) MOA a Binds to sites on the reverse transcriptase within the cell cytoplasm, preventing DNA polymerase activities needed to carry out viral DNA synthesis b Prevents the growth and replication of the viral DNA chain by blocking insertion into the host DNA c Block the activity of the enzyme protease in HIV; which is essential for the maturation of infectious virus 24 HIV/AIDS meds: Nucleoside reverse transcriptase inhibitors (NRTIs) MOA a Prevents the growth and replication of the viral DNA chain by blocking insertion into the host DNA b Block the activity of the enzyme protease in HIV; which is essential for the maturation of infectious virus c Binds to sites on the reverse transcriptase within the cell cytoplasm, preventing DNA polymerase activities needed to carry out viral DNA synthesis 25 HIV/AIDS meds: protease inhibitors a Block the activity of the enzyme protease in HIV; which is essential for the maturation of infectious virus b Prevents the growth and replication of the viral DNA chain by blocking insertion into the host DNA c Binds to sites on the reverse transcriptase within the cell cytoplasm, preventing DNA polymerase activities needed to carry out viral DNA synthesis 26 Biktarvy pharmacologic class a NRTI & INSTI b Protease inhibitors c NNRTI 27 adverse effects of Biktarvy Choose one or more answers a lactic acidosis b nephrotoxicity c nightmares, dizziness, headache d alkalosis 28 Clinically significant drug interactions for biktarvy Choose one or more answers a Acyclovir (competes for tubular secretion) b NSAIDs c furosemide Feedback 4 Loop diuretic + Gentamicin = ototoxicity 5 ACEI + Vancomycin = nephrotoxicity 6 SSRI + Erythromycin = prolonged QT interval

Antimicrobial Pharmacology

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Antimicrobial PharmacologyVersión en línea

por Amanda

If a pt has a severe gram negative infection, what antibiotic would you expect to see?

If a pt has a protozoa infection, what order would you expect for them to have?

What order would you expect to see for a pt with a gram positive infection?

What order should the nurse question for a patient with a bacterial infection with a hx of HTN currently taking furosemide?

What order should the nurse question for a pt with HTN currently taking lisinopril?

What order should the nurse question for a pt with depression who's currently taking an SSRI and a bacterial infection?

What color do you think of for a pt with tuberculosis

Which medication would you give for a pt with penicillinase-producing staphyloccoci/streptococci

Which medication is ONLY used for SERIOUS gram - infections

Which medication binds to sterols in the fungal cell wall membrane?

Which medication inhibits glucan synthesis (an enzyme present in the fungal cell wall)

Which medication would you see an order for to treat a fungal infection - ONLY IN THE HOSPITAL SETTING

Which adverse effects would you expect to see in a patient taking an antifungal medication

Amphoterincin B contraindication

Which medication class has many interactions due to it's inhibition of the P450 family of enzymes

Which order would the nurse expect to see for a patient who was diagnosed with influenza A (or avian flu) within the last 26 hours?

Which medication order should the nurse expect to see for a patient with HSV or Varicella-Zoster to inhibit the viral DNA replication?

Which medication order should the nurse expect to see for a patient with Covid-19 to inhibit the RNA polymerase enzyme that is used for viral RNA synthesis?

What should the nurse recognize is a contraindication for antiviral therapy?

HIV/AIDS meds: fusion inhibitor MOA

HIV/AIDS meds: integrase strand transfer inhibitor MOA

HIV/AIDS meds: CCR5 coreceptor antagonist MOA

HIV/AIDS meds: Nonnucleoside reverse transcriptase inhibitors (NNRTIs) MOA

HIV/AIDS meds: Nucleoside reverse transcriptase inhibitors (NRTIs) MOA

HIV/AIDS meds: protease inhibitors

Biktarvy pharmacologic class

adverse effects of Biktarvy

Clinically significant drug interactions for biktarvy