Immunology Essentials

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Immunity basics quiz

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Brandon Green

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Immunology Essentials


Immunology EssentialsVersión en línea Immunity basics quiz por Brandon Green 1 What does immune mean? a A state of susceptibility to disease b A sign of infection c A temporary illness d A state of resistance to disease 2 Who distinguished smallpox from measles and why was it important? a Louis Pasteur and Jenner combo b Abu Bakr Mohammed ibn Zakariya al-Razi c Edward Jenner d Louis Pasteur 3 What is variolation? a Exposure to cowpox only b Vaccination with weakened bacteria c Natural infection with smallpox only d Deliberate exposure to smallpox, usually via skin incision 4 Where and when were the first variolation examples in history? a 18th century Europe b 10th century Africa c 11th century in central Asia d 20th century America 5 How did Jenner develop the first smallpox vaccine? a He inoculated a child with cowpox pus and so protected against smallpox b He mixed smallpox with chickenpox c He used horsepox virus as vaccine d He used heat-killed smallpox virus 6 Why did cowpox infection protect against smallpox? a Cowpox destroys smallpox directly b Cowpox and smallpox are unrelated but boost immunity c Cowpox blocks smallpox replication in skin only d Cowpox and smallpox are closely related, enabling immune recognition 7 What does attenuation mean in vaccines? a Destroying the pathogen completely b Removing all virulence genes c Using only dead pathogens as vaccine d Weakening a live pathogen so it can replicate without causing disease 8 What is phagocytosis and who discovered it? a Complement activation; discovered by Ehrlich b Antibody production by B cells; discovered by Landsteiner c Engulfing and digesting particles; discovered by Elie Metchnikoff d T-cell receptor signaling; discovered by Claman 9 What is opsonization and who discovered it? a Complement lysis; discovered by Burnet b Neutralization of toxins; discovered by Pasteur c Enhances phagocytosis; discovered by Almroth Wright d Antibody diversity; discovered by Landsteiner 10 What was the big conclusion from Nossal and Lederberg experiments? a Antibodies are produced outside the immune system b One cell makes one antibody c Antibodies are produced by many cells per antigen d One B cell can make many different antibodies Feedback 1 Correct: immunity means resistance to disease. 2 Razi first distinguished the diseases, aiding surveillance and vaccination decisions. 3 Variolation used controlled exposure to smallpox to induce immunity. 4 Early practices occurred in Central Asia in the 11th century. 5 Cowpox exposure provided cross-protection against smallpox. 6 Shared antigens allow cross-reactive immune responses. 7 Attenuation reduces virulence while keeping immunogenicity. 8 Metchnikoff observed phagocytosis in starfish larvae. 9 Wright described how antibodies enhance phagocytosis. 10 Their work showed clonal specificity: each cell makes a single antibody type.

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Immunology Essentials

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Creada por

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Immunology EssentialsVersión en línea

por Brandon Green

What does immune mean?

Who distinguished smallpox from measles and why was it important?

What is variolation?

Where and when were the first variolation examples in history?

How did Jenner develop the first smallpox vaccine?

Why did cowpox infection protect against smallpox?

What does attenuation mean in vaccines?

What is phagocytosis and who discovered it?

What is opsonization and who discovered it?

What was the big conclusion from Nossal and Lederberg experiments?

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