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Elodie Hollman

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Quiz from Attached FileVersión en línea Unable to access the file to import questions. por Elodie Hollman 1 Starting and ending products of DNA replication a Starting product: RNA; Ending product: two identical RNA molecules b Starting product: DNA; Ending product: two identical DNA molecules c Starting product: protein; Ending product: two identical proteins 2 Starting and ending products of Transcription a Starting product: DNA; Ending product: mRNA b Starting product: RNA; Ending product: DNA c Starting product: protein; Ending product: RNA 3 Starting and ending products of Translation a Starting product: mRNA; Ending product: protein b Starting product: DNA; Ending product: RNA c Starting product: protein; Ending product: DNA 4 Where does DNA replication occur? a Nucleus b Cytoplasm c Ribosome 5 When does DNA replication occur? a G1 phase b S phase of the cell cycle c M phase 6 How does the enzyme know where to start in DNA replication? a Origins of replication b promoters c telomeres 7 How does the enzyme know where to stop in DNA replication? a Stop at centromeres b Stop at transcription start sites c Terminate at ends of chromosomes or termination sequences 8 What is the major worker (bob the builder) in DNA replication? a DNA polymerase b Helicase c RNA polymerase 9 Name the enzymes involved in DNA replication and their functions a Helicase (unwinds DNA); Primase (lays down RNA primer); DNA polymerase III (synthesizes new DNA); DNA polymerase I (replaces primer with DNA); DNA ligase (joins Okazaki fragments); Topoisomerase (relieves supercoiling) b DNA polymerase I (unwinds DNA); Primase (joins fragments); Helicase (replaces primer) c RNA polymerase (synthesizes RNA); Reverse transcriptase (synthesizes DNA from RNA); Ligase (joins fragments) 10 Name the three types of RNA and their functions a snRNA (small nuclear RNA) — splices introns; miRNA (microRNA) — regulates gene expression; siRNA — silences genes b mRNA — structural support; tRNA — transports lipids; rRNA — stores genetic info c mRNA (messenger RNA) — carries coding sequence for protein; tRNA (transfer RNA) — brings amino acids during translation; rRNA (ribosomal RNA) — forms the core of ribosome and catalyzes protein synthesis 11 Write the three steps of transcription in order a Activation, Elongation, Termination b Initiation, Termination, Translation c Initiation, Elongation, Termination 12 Write the steps of translation in order a Initiation, Termination, Elongation b Processing, Elongation, Termination c Initiation, Elongation, Termination 13 Given the DNA sequence: 5' TACGCCTAGCTCATT 3' Write the complementary DNA sequence a 3' TACGCCTAGCTCATT 5' b 3' ATGCGGATCGAGTA 5' c 5' ATGCGGATCGAGTA 3' 14 Given the DNA sequence: 5' TACGCCTAGCTCATT 3' Write the transcribed mRNA sequence. Assume the given DNA sequence is the template strand. a 5' UACGCCUAGCUCUAA 3' b 5' AUGCGGAUCGAGUAAA 3' c 5' AUGCGGAUCGAGUAA 3' 15 Translate the mRNA using the codon chart. You may use 3 letter abbreviations. a Leu-Arg-Lys-Ala-Stop b Met-Ser-Val-Gly-Stop c Met-Arg-Ile-Glu-Stop 16 Make sure you know the history of the discovery of DNA structure. Put a few notes here to remind you: a James Watson and Francis Crick - structure of DNA; Rosalind Franklin - X-ray diffraction data; Erwin Chargaff - base-pairing rules (Chargaff's rules) b Thomas Hunt Morgan - inheritance of X-linked genes; Gregor Mendel - laws of segregation; Linus Pauling - DNA triple helix c Rosalind Franklin - discovery of ribosome; James Watson and Francis Crick - protein synthesis 17 Understand how gene expression allows your body to make needed proteins. Remember our insulin example? Write the steps of gene expression of insulin here: a 1. You exercise 2. Muscle uses glucose 3. No gene expression involved b 1. Insulin is produced directly from food 2. Insulin acts without transcription c 1. You eat food 2. Digestion and absorption to raise blood glucose 3. Pancreas releases insulin 4. Insulin binds receptors and promotes glucose uptake; gene expression steps: transcription of insulin gene in pancreatic beta cells, processing of mRNA, 18 What is a mutation? a A change in the DNA sequence that can affect gene function b A harmless variation with no effect on organisms c A type of cell division 19 What is cancer? What is the difference between a benign and a malignant tumor? a Cancer only occurs in blood; benign tumors are worse than malignant b Cancer is an infection; benign tumors spread; malignant tumors do not c Cancer is uncontrolled cell growth. Benign tumors are non-cancerous and do not invade nearby tissues; malignant tumors are cancerous and can invade and spread (metastasize) 20 How does chemotherapy treat cancer? What types of cells does it target? a Chemotherapy uses drugs that kill rapidly dividing cells. It targets cancer cells, but also affects other rapidly dividing cells (e.g., hair follicles, bone marrow, gastrointestinal lining) b Chemotherapy targets only bacteria in tumors c Chemotherapy strengthens DNA; it only targets neurons

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Quiz from Attached FileVersión en línea

por Elodie Hollman

Starting and ending products of DNA replication

Starting and ending products of Transcription

Starting and ending products of Translation

Where does DNA replication occur?

When does DNA replication occur?

How does the enzyme know where to start in DNA replication?

How does the enzyme know where to stop in DNA replication?

What is the major worker (bob the builder) in DNA replication?

Name the enzymes involved in DNA replication and their functions

Name the three types of RNA and their functions

Write the three steps of transcription in order

Write the steps of translation in order

Given the DNA sequence: 5' TACGCCTAGCTCATT 3' Write the complementary DNA sequence

Given the DNA sequence: 5' TACGCCTAGCTCATT 3' Write the transcribed mRNA sequence. Assume the given DNA sequence is the template strand.

Translate the mRNA using the codon chart. You may use 3 letter abbreviations.

Make sure you know the history of the discovery of DNA structure. Put a few notes here to remind you:

Understand how gene expression allows your body to make needed proteins. Remember our insulin example? Write the steps of gene expression of insulin here:

What is a mutation?

What is cancer? What is the difference between a benign and a malignant tumor?

How does chemotherapy treat cancer? What types of cells does it target?