Relacionar Columnas GI drug Matching!!Versión en línea Match the drug to its class, MOA, adverse effect and more por Tamia Witherspoon 1 Senna 2 Loperamide 3 Sucralfate 4 Alosetron 5 Metoclopramide 6 Docusate 7 Misoprostol 8 Methylnaltrexone bromide 9 Omeprazole 10 Magnesium citrate 11 Pancrelipase 12 Sodium bicarbonate 13 cimetidine 14 Psyllium IBS and Chronic Constipation drugs Osmotic Laxatives Chemical stimulants laxatives Antacids Bulk-Forming Laxatives Gastrointestinal protect Prostaglandin histamine-2 antagonist GI Stimulants Antidiarrheal Lubricants Protein pump inhibitors Drug used to treat digestive enzyme dysfunction Opioid Antagonist 1 Omeprazole 2 Sucralfate 3 Cimetidine 4 Sodium bicarbonate 5 Pancrelipase 6 Docusate 7 Senna 8 Magnesium citrate 9 Alosetron 10 Psyllium 11 Methylnaltrexone bromide 12 Loperamide 13 Metoclopramide 14 Misoprostol Blocking opioid receptors in the GI tract w/out affecting pain relief in the brain. Restores normal bowel movement & secretion. Forms a thick paste w/ stomach acid that adheres to ulcers Draws water into intestine, promotes peristalsis Accelerates gastric emptying Stimulates peristalsis Combines w/ water in intestines to soften stool & increase bulk Blocks H2 receptors in the stomach, reducing gastric acid secretion Inhibits peristalsis & prolongs transit time. Facilities the digestion of fat, carbohydrates, and protein in the GI tract Rises firmness in stool & lowers urgency Draws water into stool, resulting in softer stool Neutralizes stomach acid Lowers gastric acid secretion Lowers stomach acid secretion, raises production of protective mucus & bicarbonate = causes uterine contractions 1 Misoprostol 2 Omeprazole 3 Magnesium citrate 4 Pancrelipase 5 Methylnaltrexone bromide 6 Loperamide 7 Psyllium 8 Alosetron 9 Cimetidine 10 Metoclopramide 11 Sucralfate 12 Senna 13 Docusate 14 Sodium bicarbonate Toxic megacolon (rare but serious), Mild cramping, nausea, vomiting. Cardiac arrest, Gynecomatia, Somnolence Mild cramping, Frequent use can interfere w/ the absorption of fat-soluble vitamins A, D, E, & K long term use=deficiency. Diarrhea, Nausea, Abdominal pain Cathartic dependence Hyper magnesium, cramping, bloating, diarrhea. Constipation, Diarrhea, Fluid retention, Electrolyte issues Constipation, Vertigo, Insomnia, Indigestion Constipation, ischemic colitis Severe abdominal pain or diarrhea➡️may indicate GI perforation or need for dose reduction/discontinuation Dysmenorrhea (painful & severe menstrual cramps), irregular periods (hypermenorrhea), miscarriage Rigidity, tremors, restlessness. Tardive dyskinesia, seizures, Parkinson’s-like symptoms, low BP & HR ( due to parasympathetic stimulation) C.diff, bone fractures, magnesium, calcium, B12 deficiency 1 Sodium bicarbonate 2 Pancrelipase 3 Metoclopramide 4 Docusate 5 Omeprazole 6 Senna 7 Loperamide 8 Methylnaltrexone bromide 9 Prostaglandin 10 Magnesium citrate 11 Alosetron 12 Cimetidine 13 Sucralfate 14 Psyllium Chronic noncancer pain Duodenal ulcers Duodenal & gastric ulcers, GERD Zollinger-Ellison Relieve different levels of diarrhea (acute, chronic, irritable bowel syndrome (IBS), reducing ileostomy discharge Draws water into stool, resulting in softer stool. Duodenal & gastric ulcers, GERD, Zollinger-Ellison syndrome IBS w/ diarrhea Gastroparesis, Nausea, vomiting GERD. Prevention of gastric ulcers in pts taking NSAIDs. Also induces labor by ripening the cervix. Peptic ulcer disease, GERD Short term treatment of constipation. Bowel prep before surgery or procedure. Constipation, prevention of straining, and management of chronic watery diarrhea. Pancreatic insufficiency related to pancreatitis, cystic fibrosis, GI bypass surgery. Constipation, bowel prep before a surgery or procedure. 1 Docusate 2 Omeprazole 3 Psyllium 4 Alosetron 5 Metoclopromide 6 Magnesium citrate 7 Senna 8 Sodium Bicarbonate 9 Cimetidine 10 Pancrelipase 11 Methylnaltrexone bromide 12 Sucralfate 13 Loperamide Swallow whole!, report diarrhea, abdominal pain, and bloody stools. Take before meals preferably in the morning. Try using only for short-term Take immediately before or w/ meals & snacks, swallow whole!, if pill is difficult to swallow open pill & sprinkle on acidic food. Always follow label directions carefully, report prolonged diarrhea or cramping, short term relief only, raise adequate fluid intake. Fluid & electrolyte replacement during diarrhea episodes. Avoid bismuth in children or teens w/ viral infections. Report unusual facial or body movements, restlessness, or muscle stiffness immediately. Symptom managing, not a cure, hydration and dietary fiber as tolerated Take 1 hr before meals & at bedtime (4 times a day), increase fluid & fiber intake, swallow whole! Don’t Double up, report black/tarry stools, avoid caffeine, and take before meals or at bedtime Take w/ a full glass of water, increase fiber & fluid intake, short term use only, results may take several days. Take w/ a full glass of water, increase fiber, fluid, & exercise, don’t take before bedtime, report persistent constipation or abdominal pain. Report severe abdominal pain, nausea, or diarrhea. Hydration & diet changes to promote natural bowel motility. Increase fluids, fiber, & activity. Don’t use daily to avoid dependence, report severe abdominal pain or persistent constipation. Take after meals & at bedtime, 1-2 hrs. before or after other medications.