Gluconeogenesis Quiz

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For first MBBS students

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Jayakala Thankiah

India

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Gluconeogenesis QuizVersión en línea For first MBBS students por Jayakala Thankiah 1 Which of the following is the key regulatory enzyme of gluconeogenesis? a Pyruvate carboxylase b Hexokinase c Phosphofructokinase-1 d Glycogen synthase 2 A patient with biotin deficiency may have impaired gluconeogenesis due to defective activity of which enzyme? a Pyruvate carboxylase b Phosphoenolpyruvate carboxykinase c Fructose-1,6-bisphosphatase d Glucose-6-phosphatase 3 Which of the following conditions will most likely stimulate gluconeogenesis? a Prolonged fasting b Increased insulin levels c High blood glucose levels d Increased availability of fructose-2,6-bisphosphate 4 A researcher is studying the effects of a new drug that inhibits phosphoenolpyruvate carboxykinase (PEPCK). What would be the expected metabolic consequence of this inhibition? a Decreased hepatic glucose production b Increased conversion of pyruvate to glucose c Increased glycolysis in liver cells d Increased utilization of glycogen stores 5 Why is gluconeogenesis not a simple reversal of glycolysis? a Because three irreversible steps in glycolysis need to be bypassed by different enzymes b Because glycolysis occurs in the cytoplasm while gluconeogenesis occurs in mitochondria c Because gluconeogenesis requires oxygen while glycolysis does not d Because glycolysis produces ATP whereas gluconeogenesis does not

Gluconeogenesis QuizVersión en línea

For first MBBS students

por Jayakala Thankiah

Which of the following is the key regulatory enzyme of gluconeogenesis?

Pyruvate carboxylase

Hexokinase

Phosphofructokinase-1

Glycogen synthase

A patient with biotin deficiency may have impaired gluconeogenesis due to defective activity of which enzyme?

Pyruvate carboxylase

Phosphoenolpyruvate carboxykinase

Fructose-1,6-bisphosphatase

Glucose-6-phosphatase

Which of the following conditions will most likely stimulate gluconeogenesis?

Prolonged fasting

Increased insulin levels

High blood glucose levels

Increased availability of fructose-2,6-bisphosphate

A researcher is studying the effects of a new drug that inhibits phosphoenolpyruvate carboxykinase (PEPCK). What would be the expected metabolic consequence of this inhibition?

Decreased hepatic glucose production

Increased conversion of pyruvate to glucose

Increased glycolysis in liver cells

Increased utilization of glycogen stores

Why is gluconeogenesis not a simple reversal of glycolysis?

Because three irreversible steps in glycolysis need to be bypassed by different enzymes

Because glycolysis occurs in the cytoplasm while gluconeogenesis occurs in mitochondria

Because gluconeogenesis requires oxygen while glycolysis does not

Because glycolysis produces ATP whereas gluconeogenesis does not

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Gluconeogenesis Quiz

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Gluconeogenesis QuizVersión en línea

por Jayakala Thankiah

Which of the following is the key regulatory enzyme of gluconeogenesis?

A patient with biotin deficiency may have impaired gluconeogenesis due to defective activity of which enzyme?

Which of the following conditions will most likely stimulate gluconeogenesis?

A researcher is studying the effects of a new drug that inhibits phosphoenolpyruvate carboxykinase (PEPCK). What would be the expected metabolic consequence of this inhibition?

Why is gluconeogenesis not a simple reversal of glycolysis?

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