Relacionar Columnas HIV Drug Mechanisms of ActionVersión en línea Match the HIV drug class with its mechanism of action por Ethan Lentz 1 Nucleoside reverse transcriptase inhibitors 2 Integrase inhibitors 3 HIV Protease inhibitors 4 Non-nucleoside reverse transcriptase inhibitors 5 CYP3A4 inhibitors (protease inhibitor boosters) Allosterically bind to reverse transcriptase to reduce molecular motion in the enzyme and inhibit its function Inhibit destruction of protease inhibitors by host metabolism Inhibits HIV integrase enzyme preventing insertion of viral cDNA into the host genome Bind to the active site of HIV proteases preventing the creation of new viral particles Acts as a substrate for reverse transcriptase, inserting into viral DNA and blocking replication at 3'-OH
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