Relacionar Columnas HIV Drug Mechanisms of ActionVersión en línea Match the HIV drug class with its mechanism of action por Ethan Lentz 1 CYP3A4 inhibitors (protease inhibitor boosters) 2 Integrase inhibitors 3 Nucleoside reverse transcriptase inhibitors 4 Non-nucleoside reverse transcriptase inhibitors 5 HIV Protease inhibitors Allosterically bind to reverse transcriptase to reduce molecular motion in the enzyme and inhibit its function Acts as a substrate for reverse transcriptase, inserting into viral DNA and blocking replication at 3'-OH Bind to the active site of HIV proteases preventing the creation of new viral particles Inhibits HIV integrase enzyme preventing insertion of viral cDNA into the host genome Inhibit destruction of protease inhibitors by host metabolism
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