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Fill in the Blanks: Krebs Cycle

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Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game!

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Fill in the Blanks: Krebs CycleVersión en línea

Test your knowledge of the Krebs cycle by filling in the missing words in this interactive game!

por Bio Innovators
1

Tricarboxylic acid Krebs cycle matrix transport chain FADH2 electron NADH

is also known as Citric acid cycle or cycle . It occurs in the of mitochondria to provide in the form of and that are used in electron .

2

CoA citrate removal Condensation oxaloacetate, OAA Citrate isocitrate pyruvate oxidation rearranged Isomerization addition

1 .
Acetyl - CoA from removes group . The remaining acetyl combines with to form .

2 .
is then to its isomer , by the of one water molecule and of one water molecule .

3

reduced CO2 transferring 5-carbon NAD decarboxylation ketoglutarate H

3 . Oxidative decarboxylation
Isocitrate loses a molecule of , forming a molecule ( ) . The remaining 5 - carbon is oxidized into ? - , by their electrons and + to NAD + . + is to NADH + H + .

4

ketoglutarate oxidized succinyl CoA NADH 4C molecule CO2 Coenzyme A

4 . Oxidative decarboxylation
? - lose a molecule of forming a 4C molecule . The remaining is before combining with , to form . NAD + is reduced to + H + .

5

phosphorylation FAD GTP fumarate two hydrogen atoms phosphate group Succinate FAD CoA energy ATP Substrate level GTP ADP succinate FADH

5 . phosphorylation
Succinyl - CoA loses and converted to . The released is used in the of GDP to form . then transfer its to to form .

6 . Oxidation
is oxidized to , by transferring to . is reduced to .

6

Fumarate regenerated malate oxaloacetate water molecule oxidized Reduction rearranged Malate NADH

7 . Hydration
is into by addition of one .

8 . Oxidation
is . of NAD + to + H + occurs and is .

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