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5.2 DNA Replication

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Complete these events taking place in eukaryotic DNA replication

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5.2 DNA ReplicationVersión en línea

Complete these events taking place in eukaryotic DNA replication

por Helmina Kmrzmn
1

RNA towards free complementary swiveling SSBP template discontinously continuously 3' semiconservative helicase stabilise Okazaki III phosphodiester parent ligase primers DNA fork strain

DNA untwist and unwind double stranded DNA ( dsDNA ) .
Single stranded DNA binding proteins ( ) will be recruited to the unwound dsDNA .
The untwisting of the double helix creates ahead of the replication fork .
Topoisomerase will relieve the strain by breaking , and rejoining DNA strand .
Both strands of the parental DNA molecule will become strands .

RNA primase will synthesis , using the parental DNA strands as template .
DNA polymerase adds DNA nucleotides to the end of the RNA primer .
DNA nucleotides are added to the growing DNA strand by polymerase III by forming bonds .
DNA polymerase III will continue adding new nucleotides to the growing DNA strands in the 5' - 3' direction .
This means that the DNA nucleotides can only be added on to the 3' end of a growing DNA strand .

There are two types of DNA strands synthesised by DNA polymerase : leading and lagging strands .

The leading strand elongates in the 5' - 3' direction the replication fork . As a result , leading strands only require one primer .
Meanwhile , the lagging strand elongates in 5' - 3' direction away from the replication . As a result , lagging strands require multiple RNA primers for each of their fragments .

Eventually , DNA polymerase I will replace all RNA primers with nucleotides .
Finally , DNA will seal any gaps between DNA fragments by forming phosphodiester bonds
Two identical DNA molecules are produced .
Each of these DNA molecules comprised of one strand and one new strand .
This mode of replication is known as the model .

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