Relacionar Columnas Cholesterol pharmacologyVersión en línea Cholesterol pharmacology por Ashleigh Pell 1 statin warning 2 standard statin 3 statin side effects 4 with less cholesterol synthesis, what does the liver do? 5 statin with less drug interactions 6 What does the enzyme HMG-CoA do? 7 statin indication 8 What statins do, and where 9 most potent statin increases hepatic synthesis of cholesterol simvastatin atorvastatin increases the uptake of low-density lipoprotein (LDL) from the blood pravastatin inhibit HMG-CoA reductase in the liver Grapefruit inhibits cytochrome P450, increasing statin bioavailability. myalgia/headache/GI symptoms high lipids / LDL 1 fenofibrate activates 2 ezetimisbe side effect 3 ezetimibe inhibits 4 alirocumab indication 5 fenofibrate contra-indication 6 Alirocumab side effects 7 fenofibrate caution 8 Fenofibrate indication 9 fenofibrate causes lipolysis because 10 Alirocumab inhibits 11 fenofibrate side effects myotoxicity if improper dose or renal impairment. PPARα's genes code for peroxisomes which participate in lipolysis high serum triglycerides nuclear receptor PPARα which begins gene transcription and translation flu-like symptoms weakness/GI upset/headaches inhibits PCSK9, a liver protein that regulates/breaks down LDL receptors GI upset/vomiting gall bladder disease, pancreatitis familial hypercholesterolaemia, high risk, statins and ezetimibe ineffective intestinal cholesterol absorption
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