Relacionar Columnas Cholesterol pharmacologyVersión en línea Cholesterol pharmacology por Ashleigh Pell 1 with less cholesterol synthesis, what does the liver do? 2 standard statin 3 statin side effects 4 statin warning 5 statin with less drug interactions 6 What statins do, and where 7 statin indication 8 most potent statin 9 What does the enzyme HMG-CoA do? Grapefruit inhibits cytochrome P450, increasing statin bioavailability. increases hepatic synthesis of cholesterol high lipids / LDL myalgia/headache/GI symptoms pravastatin simvastatin increases the uptake of low-density lipoprotein (LDL) from the blood inhibit HMG-CoA reductase in the liver atorvastatin 1 ezetimisbe side effect 2 fenofibrate causes lipolysis because 3 alirocumab indication 4 fenofibrate activates 5 Alirocumab side effects 6 Alirocumab inhibits 7 Fenofibrate indication 8 fenofibrate caution 9 fenofibrate side effects 10 ezetimibe inhibits 11 fenofibrate contra-indication PPARα's genes code for peroxisomes which participate in lipolysis gall bladder disease, pancreatitis weakness/GI upset/headaches high serum triglycerides familial hypercholesterolaemia, high risk, statins and ezetimibe ineffective myotoxicity if improper dose or renal impairment. inhibits PCSK9, a liver protein that regulates/breaks down LDL receptors intestinal cholesterol absorption flu-like symptoms GI upset/vomiting nuclear receptor PPARα which begins gene transcription and translation
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