Relacionar Columnas Cholesterol pharmacologyVersión en línea Cholesterol pharmacology por Ashleigh Pell 1 statin side effects 2 with less cholesterol synthesis, what does the liver do? 3 What statins do, and where 4 statin with less drug interactions 5 statin indication 6 most potent statin 7 statin warning 8 standard statin 9 What does the enzyme HMG-CoA do? high lipids / LDL pravastatin inhibit HMG-CoA reductase in the liver simvastatin myalgia/headache/GI symptoms Grapefruit inhibits cytochrome P450, increasing statin bioavailability. atorvastatin increases the uptake of low-density lipoprotein (LDL) from the blood increases hepatic synthesis of cholesterol 1 alirocumab indication 2 ezetimibe inhibits 3 fenofibrate side effects 4 Alirocumab side effects 5 ezetimisbe side effect 6 fenofibrate activates 7 fenofibrate caution 8 fenofibrate causes lipolysis because 9 Alirocumab inhibits 10 fenofibrate contra-indication 11 Fenofibrate indication myotoxicity if improper dose or renal impairment. inhibits PCSK9, a liver protein that regulates/breaks down LDL receptors PPARα's genes code for peroxisomes which participate in lipolysis GI upset/vomiting familial hypercholesterolaemia, high risk, statins and ezetimibe ineffective high serum triglycerides nuclear receptor PPARα which begins gene transcription and translation flu-like symptoms gall bladder disease, pancreatitis intestinal cholesterol absorption weakness/GI upset/headaches