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Studies have indicated that CYLD encodes a deubiquitinating enzyme ____________________ negatively regulates the
nuclear factor ( NF ) ? kappaB and c - Jun N - terminal kinase ( JNK ) pathways . Due to the ____________________ of
significant numbers of Merkel cells within the tumor ____________________ and the detection of a sheath of CD34 -
positive dendrocytes ____________________ the tumor nests , it appears that trichoepithelioma differentiates toward ____________________
derives from hair structures , particularly the hair bulge . Rare ____________________ of tumors resembling
trichoepithelioma ____________________ been reported ____________________ animals .