Sebaceous
glands
are
____________________
throughout
the
skin
except
____________________
the
palms
and
soles
.
They
exist
as
a
component
of
the
pilosebaceous
unit
____________________
,
less
frequently
,
open
directly
to
the
epithelial
surface
in
areas
of
modified
skin
,
including
the
lips
and
buccal
mucosa
(
as
Fordyce
spots
)
,
glans
penis
or
clitoris
(
as
Tyson
glands
)
,
areolae
(
as
Montgomery
glands
)
,
____________________
eyelids
(
as
meibomian
glands
)
.
The
largest
and
greatest
numbers
____________________
sebaceous
glands
are
found
on
the
face
,
chest
,
back
,
and
the
upper
outer
arms
.
These
holocrine
glands
are
____________________
of
acini
attached
to
a
common
excretory
duct
.
The
life
cycle
of
a
sebocyte
,
the
cells
that
form
the
sebaceous
gland
,
begins
____________________
the
periphery
of
the
gland
in
the
highly
mitotic
basal
cell
layer
.
As
sebocytes
differentiate
and
mature
,
____________________
accumulate
increasing
amounts
of
lipid
and
migrate
toward
the
central
excretory
duct
.
The
mature
sebocytes
complete
their
life
cycle
at
the
central
duct
and
disintegrate
,
releasing
their
lipid
contents
as
sebum
.
The
turnover
time
____________________
sebocyte
production
____________________
disintegration
is
approximately
1
month
.
