Premature
rupture
of
membranes
(
PROM
)
____________________
to
a
patient
who
is
beyond
37
weeks'
gestation
____________________
has
presented
with
rupture
of
____________________
(
ROM
)
prior
to
the
onset
of
labor
.
Preterm
____________________
rupture
of
membranes
(
PPROM
)
is
ROM
prior
____________________
37
weeks'
gestation
.
Spontaneous
preterm
rupture
____________________
the
membranes
(
SPROM
)
is
ROM
____________________
or
with
the
onset
of
labor
occurring
prior
to
37
____________________
.
Prolonged
ROM
is
____________________
ROM
that
persists
for
more
than
24
hours
and
prior
to
the
onset
of
____________________
.
At
term
,
programmed
cell
death
and
____________________
of
catabolic
enzymes
,
such
as
____________________
and
mechanical
____________________
,
result
in
ruptured
membranes
.
Preterm
PROM
occurs
____________________
due
to
the
same
mechanisms
and
premature
____________________
of
these
pathways
.
However
,
early
PROM
also
appears
to
____________________
linked
to
underlying
pathologic
processes
,
most
likely
due
to
inflammation
and
/
or
infection
of
the
membranes
.
Clinical
____________________
associated
with
preterm
PROM
include
low
____________________
status
,
low
body
mass
index
,
tobacco
use
,
preterm
labor
____________________
,
urinary
tract
infection
,
vaginal
bleeding
at
any
time
in
pregnancy
,
____________________
,
and
amniocentesis
.
