The
developmental
theory
of
____________________
accounts
for
several
clinical
and
pathologic
features
,
including
occurrence
in
older
individuals
,
location
in
the
cecum
and
proximal
____________________
colon
,
and
prominent
submucosal
veins
that
dilate
after
____________________
the
muscularis
propria
.
In
addition
,
it
also
accounts
for
the
lack
of
pathologic
changes
____________________
arterioles
supplying
vascular
ectasias
and
the
absence
of
any
mucosal
lesion
associated
with
____________________
.
Previous
studies
demonstrating
that
colonic
motility
,
increased
tension
in
the
bowel
wall
,
and
increased
intraluminal
pressure
____________________
diminish
venous
flow
lend
further
support
to
this
theory
.
Dilated
submucosal
veins
have
____________________
one
of
the
most
consistent
histologic
____________________
and
may
represent
the
earliest
abnormality
in
colonic
angiodysplasia
.
This
histologic
feature
supports
the
theory
____________________
chronic
venous
obstruction
in
the
genesis
of
angiodysplasia
.
Of
note
,
the
aforementioned
pathophysiologic
mechanisms
responsible
____________________
the
development
of
cecal
lesions
are
____________________
to
apply
to
lesions
in
the
upper
GI
tract
,
despite
being
morphologically
identical
.
