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Practice Essentials
Chronic obstructive pulmonary disease ( COPD ) is estimated to ____________________ 32 million persons in the United States and is the third leading cause of ____________________ in this country . [ 1 ] Patients typically have symptoms of chronic bronchitis and emphysema , but the classic triad also includes ____________________ or a combination of the above ( see the image below ) .
Chronic bronchitis is ____________________ clinically as the presence of a chronic productive ____________________ for 3 months during each ____________________ 2 consecutive years ( other causes of cough ____________________ excluded ) .
Emphysema is defined pathologically as ____________________ abnormal , permanent enlargement of the air spaces distal to the ____________________ bronchioles , accompanied by destruction of their walls and ____________________ obvious fibrosis .