Hydroxyurea
Vincristine
Cyclophosphamide
Methotrexate
Etoposide
Cisplatin
Imatinib
Irinotecan
Doxorubicin
Bleomycin
Paclitaxel
Pembrolizumab
Gemcitabine
Bevacizumab
Erlotinib
Rituximab
Free radicals break DNA
Monoclonal Ab blocks VEGF
Inhibits dihydrofolate reducatse
Monoclonal Ab Inhibits PD-1
BCR-ABL - Tyrosine Kinase Inhibitor
Promotes microtubule formation then prevents their degradation
Inhibits microtubule formation
Monoclonal Ab causes CD20+ B-Cell apoptosis
Inhibits topoisomerase II
Free radicals break DNA & Topoisomerase II inhibitor
Inhibits ribonucleotide reductase & increases HbF levels
Cross links DNA, inhibiting synthesis
Inhibits ribonucleotide reductase & DNA polymerase
Cross links DNA, inhibiting synthesis
Inhibits topoisomerase I & causes double strand DNA breaks
Tyrosine Kinase - EGFR inhibitor