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Alpha ____________________ receptors are located in the ____________________ membrane of smooth muscles . It is the cause of ____________________ of ____________________ + channels . This causes ____________________ + influx and therefore ____________________ of smooth muscle in the PM . Therefore smooth muscle will ____________________ . Alpha ____________________ receptors are located on the ____________________ membranes . It opens ____________________ + channels . Therefore it causes ____________________ of the presynaptic membrane . This will ____________________ synaptic transmission .